Immunohistochemical Staining of Feline Malignant Fibrous Histiocytomas
نویسندگان
چکیده
منابع مشابه
Malignant fibrous histiocytomas of salivary glands.
The light microscopic, immunohistological and ultrastructural findings in two cases of malignant fibrous histiocytoma arising in salivary glands are presented and the features of seven previously reported cases are reviewed. This neoplasm is extremely rare in this site and may pose problems in diagnosis. It has to be distinguished from other spindled cell tumours, in particular from epithelial ...
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PURPOSE Soft tissue sarcomas (STS) account for less than 1% of all malignancies and constitute a heterogeneous tumor entity in which malignant fibrous histiocytomas (MFH) represent one-third and are characterized by a lack of type-specific differentiation. A defective mismatch repair (MMR) system cause the familial cancer syndrome hereditary non-polyposis colorectal cancer (HNPCC), and since oc...
متن کاملProposal of a new grading system for malignant fibrous histiocytomas.
The proposed grading system for malignant fibrous histiocytomas (MFH) comprises 3 grades of malignancy. Analogous to other grading systems, the system includes the factors of mitotic rate and necrosis. In addition to these two factors, the concept of cellularity was included. The prognostic relevance of the grading systems published by Costa, Coindre, van Unnik, Pezzi and Tsujimoto as well as t...
متن کاملTwo different types of malignant fibrous histiocytomas from pet dogs
We describe 2 cases of malignant fibrous histiocytomas (MFHs) that spontaneously developed in young pet dogs. To classify these tumors, we applied a panel of antibodies (vimentin, desmin, alpha-SMA, and ED1) and Azan staining for collagen. The MFHs were most consistent with osteoclastlike giant and inflammatory cell types. The first case had positive staining for ED1 and vimentin, and given the...
متن کاملMalignant fibrous histiocytomas and H-ras-1 oncogene point mutations.
AIMS To investigate the types and the frequencies of H-ras-1 gene mutations in malignant fibrous histiocytomas. METHODS Thirty five samples of malignant fibrous histiocytoma tissue were searched for point mutations within "hot spot" codons 12 and 13 of the H-ras-1 oncogene by the specific "nested" polymerase chain reaction followed by restriction fragment length polymorphism (PCR-RFLP) and a ...
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ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 1994
ISSN: 0300-9858,1544-2217
DOI: 10.1177/030098589403100202